Local DISEMBL setup

# download Tisean
wget http://www.mpipks-dresden.mpg.de/~tisean/TISEAN_2.1.tar.gz
tar xvf TISEAN_2.1.tar.gz
cd TISEAN_2.1 

# we need to let TISEAN know that we have gfortran installed
export FC=gfortran
./configure
make

I did get some errors due to malloc.h being deprecated on the Mac, however, disembl only needed sav_gol, which compiled without trouble.

Next, move onto the disembl setup:

cd ..
wget http://dis.embl.de/DisEMBL-1.4.tgz
tar xvf DisEMBL-1.4.tgz 
cd DisEMBL-1.4
cp ../TISEAN_2.1/source_c/sav_gol .
gcc -O3 disembl.c -o disembl

Lastly, set correct paths to the neural net binary and savgol at the top of the script DisEMBL.py.

… and run!

./DisEMBL.py 8 8 4 1.2 1.4 1.2 example.fasta scores